Ontology highlight
ABSTRACT:
SUBMITTER: Gerbaix M
PROVIDER: S-EPMC5453937 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Gerbaix Maude M Gnyubkin Vasily V Farlay Delphine D Olivier Cécile C Ammann Patrick P Courbon Guillaume G Laroche Norbert N Genthial Rachel R Follet Hélène H Peyrin Françoise F Shenkman Boris B Gauquelin-Koch Guillemette G Vico Laurence L
Scientific reports 20170601 1
The weightless environment during spaceflight induces site-specific bone loss. The 30-day Bion-M1 mission offered a unique opportunity to characterize the skeletal changes after spaceflight and an 8-day recovery period in mature male C57/BL6 mice. In the femur metaphysis, spaceflight decreased the trabecular bone volume (-64% vs. Habitat Control), dramatically increased the bone resorption (+140% vs. Habitat Control) and induced marrow adiposity invasion. At the diaphysis, cortical thinning asso ...[more]