Ontology highlight
ABSTRACT:
SUBMITTER: Goldberg JD
PROVIDER: S-EPMC5454777 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Leukemia & lymphoma 20170110 8
Infection, relapse, and GVHD can complicate allogeneic hematopoietic stem cell transplantation (allo-HSCT). Although the effect of poor immune recovery on infection risk is well-established, there are limited data on the effect of immune reconstitution on relapse and survival, especially following T-cell depletion (TCD). To characterize the pattern of immune reconstitution in the first year after transplant and its effects on survival and relapse, we performed a retrospective study in 375 recipi ...[more]