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Chemical Diversity, Biological Activity, and Genetic Aspects of Three Ocotea Species from the Amazon.

ABSTRACT: Ocotea species present economic importance and biological activities attributed to their essential oils (EOs) and extracts. For this reason, various strategies have been developed for their conservation. The chemical compositions of the essential oils and matK DNA sequences of O. caudata, O. cujumary, and O. caniculata were subjected to comparison with data from O. floribunda, O. veraguensis, and O. whitei, previously reported. The multivariate analysis of chemical composition classified the EOs into two main clusters. Group I was characterized by the presence of α-pinene (9.8-22.5%) and β-pinene (9.7-21.3%) and it includes O. caudata, O. whitei, and O. floribunda. In group II, the oils of O. cujumary and O. caniculata showed high similarity due amounts of β-caryophyllene (22.2% and 18.9%, respectively). The EO of O. veraguensis, rich in p-cymene (19.8%), showed minor similarity among all samples. The oils displayed promising antimicrobial and cytotoxic activities against Escherichia coli (minimum inhibitory concentration (MIC) < 19.5 µg·mL-1) and MCF-7 cells (median inhibitory concentration (IC50) ≅ 65.0 µg·mL-1), respectively. The analysis of matK gene displayed a good correlation with the main class of chemical compounds present in the EOs. However, the matK gene data did not show correlation with specific compounds.

SUBMITTER: da Silva JK

PROVIDER: S-EPMC5454990 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature

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Chemical Diversity, Biological Activity, and Genetic Aspects of Three Ocotea Species from the Amazon.

da Silva Joyce Kelly JK da Trindade Rafaela R Moreira Edith Cibelle EC Maia José Guilherme S JGS Dosoky Noura S NS Miller Rebecca S RS Cseke Leland J LJ Setzer William N WN

International journal of molecular sciences 20170518 5

Ocotea species present economic importance and biological activities attributed to their essential oils (EOs) and extracts. For this reason, various strategies have been developed for their conservation. The chemical compositions of the essential oils and matK DNA sequences of O. caudata, O. cujumary, and O. caniculata were subjected to comparison with data from O. floribunda, O. veraguensis, and O. whitei, previously reported. The multivar ...[more]

PMID: 28524091

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Dataset Information

Chemical Diversity, Biological Activity, and Genetic Aspects of Three Ocotea Species from the Amazon.

Publications

Chemical Diversity, Biological Activity, and Genetic Aspects of Three Ocotea Species from the Amazon.

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