Ontology highlight
ABSTRACT:
SUBMITTER: Rinsma NF
PROVIDER: S-EPMC5455000 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Rinsma Nicolaas F NF Farré Ricard R Troost Fred J FJ Elizalde Montserrat M Keszthelyi Daniel D Helyes Zsuzsanna Z Masclee Ad A AA Conchillo José M JM
International journal of molecular sciences 20170519 5
In the absence of visible mucosal damage, it is hypothesized that the esophageal mucosal barrier is functionally impaired in patients with non-erosive reflux disease (NERD). The aim of the present study was to perform an exploratory analysis of the mucosal barrier in NERD compared to erosive esophagitis (EE) and controls. A second aim was to explore <i>TRPV1</i> gene transcription in relation to the mucosal barrier function and heartburn symptoms. In this prospective study, 10 NERD patients, 11 ...[more]