Ontology highlight
ABSTRACT:
SUBMITTER: Marakhouski KY
PROVIDER: S-EPMC5457029 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Marakhouski K Y KY Karaseva G A GA Ulasivich D N DN Marakhouski Y Kh YK
Clinical medicine insights. Gastroenterology 20170531
<h4>Aim</h4>To compare the efficacy and safety of omeprazole-domperidone combination vs omeprazole monotherapy in gastroesophageal reflux disease (GERD).<h4>Methods</h4>In a comparative, randomized controlled, phase 4 study, outpatients with GERD were randomly allocated to either group 1 (omeprazole 20 mg + domperidone 30 mg) or group 2 (omeprazole 20 mg) in an equal ratio; 2 capsules daily in the morning were administered for 8 weeks.<h4>Results</h4>Sixty patients were enrolled. Esophagitis rev ...[more]