Ontology highlight
ABSTRACT:
SUBMITTER: Engmann NJ
PROVIDER: S-EPMC5457346 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Engmann Natalie J NJ Scott Christopher G CG Jensen Matthew R MR Ma Lin L Brandt Kathleen R KR Mahmoudzadeh Amir Pasha AP Malkov Serghei S Whaley Dana H DH Hruska Carrie B CB Wu Fang Fang FF Winham Stacey J SJ Miglioretti Diana L DL Norman Aaron D AD Heine John J JJ Shepherd John J Pankratz V Shane VS Vachon Celine M CM Kerlikowske Karla K
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20170201 6
<b>Background:</b> Reductions in breast density with tamoxifen and aromatase inhibitors may be an intermediate marker of treatment response. We compare changes in volumetric breast density among breast cancer cases using tamoxifen or aromatase inhibitors (AI) to untreated women without breast cancer.<b>Methods:</b> Breast cancer cases with a digital mammogram prior to diagnosis and after initiation of tamoxifen (<i>n</i> = 366) or AI (<i>n</i> = 403) and a sample of controls (<i>n</i> = 2170) we ...[more]