Computing Substrate Selectivity in a Peptide Transporter.
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ABSTRACT:
SUBMITTER: Colas C
PROVIDER: S-EPMC5457801 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Publications
Computing Substrate Selectivity in a Peptide Transporter.
Colas Claire C Smith David E DE Schlessinger Avner A
Cell chemical biology 20160201 2
The human proton-coupled peptide transporter 1 (PepT1) is responsible for the absorption of di- and tri-peptides from the diet and peptide-like drugs. In this issue of Cell Chemical Biology, Samsudin et al. (2016) use an integrated computational and experimental approach to provide new insights into understanding substrate selectivity of PepTSt, a prokaryotic homolog of the human PepT1. ...[more]
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