Ontology highlight
ABSTRACT:
SUBMITTER: Yasuda K
PROVIDER: S-EPMC5458228 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Yasuda Kazuyo K Hirohashi Yoshihiko Y Mariya Tasuku T Murai Aiko A Tabuchi Yuta Y Kuroda Takafumi T Kusumoto Hiroki H Takaya Akari A Yamamoto Eri E Kubo Terufumi T Nakatsugawa Munehide M Kanaseki Takayuki T Tsukahara Tomohide T Tamura Yasuaki Y Hirano Hiroshi H Hasegawa Tadashi T Saito Tsuyoshi T Sato Noriyuki N Torigoe Toshihiko T
Oncotarget 20170501 19
Cancer stem-like cells (CSCs)/ cancer-initiating cells (CICs) are defined by their higher tumor-initiating ability, self-renewal capacity and differentiation capacity. CSCs/CICs are resistant to several therapies including chemotherapy and radiotherapy. CSCs/CICs thus are thought to be responsible for recurrence and distant metastasis, and elucidation of the molecular mechanisms of CSCs/CICs are essential to design CSC/CIC-targeting therapy. In this study, we analyzed the molecular aspects of gy ...[more]