Ontology highlight
ABSTRACT:
SUBMITTER: Jolly MK
PROVIDER: S-EPMC5460282 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
NPJ breast cancer 20170606
Metastases claim more than 90% of cancer-related patient deaths and are usually seeded by a subset of circulating tumor cells shed off from the primary tumor. In circulation, circulating tumor cells are found both as single cells and as clusters of cells. The clusters of circulating tumor cells, although many fewer in number, possess much higher metastatic potential as compared to that of individual circulating tumor cells. In this review, we highlight recent insights into molecular mechanisms t ...[more]