Ontology highlight
ABSTRACT:
SUBMITTER: Antell GC
PROVIDER: S-EPMC5460428 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Antell Gregory C GC Dampier Will W Aiamkitsumrit Benjamas B Nonnemacher Michael R MR Pirrone Vanessa V Zhong Wen W Kercher Katherine K Passic Shendra S Williams Jean J Liu Yucheng Y James Tony T Jacobson Jeffrey M JM Szep Zsofia Z Wigdahl Brian B Krebs Fred C FC
International journal of genomics 20170517
Vpr is an HIV-1 accessory protein that plays numerous roles during viral replication, and some of which are cell type dependent. To test the hypothesis that HIV-1 tropism extends beyond the envelope into the <i>vpr</i> gene, studies were performed to identify the associations between coreceptor usage and Vpr variation in HIV-1-infected patients. Colinear HIV-1 Env-V3 and Vpr amino acid sequences were obtained from the LANL HIV-1 sequence database and from well-suppressed patients in the Drexel/T ...[more]