The Role of Astrocyte Dysfunction in Parkinson's Disease Pathogenesis.
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ABSTRACT:
SUBMITTER: Booth HDE
PROVIDER: S-EPMC5462417 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Publications
The Role of Astrocyte Dysfunction in Parkinson's Disease Pathogenesis.
Booth Heather D E HDE Hirst Warren D WD Wade-Martins Richard R
Trends in neurosciences 20170517 6
Astrocytes are the most populous glial subtype and are critical for brain function. Despite this, historically there have been few studies into the role that they may have in neurodegenerative diseases, such as Parkinson's disease (PD). Recently, however, several studies have determined that genes known to have a causative role in the development of PD are expressed in astrocytes and have important roles in astrocyte function. Here, we review these recent developments and discuss their impact on ...[more]
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