Ontology highlight
ABSTRACT:
SUBMITTER: Wang J
PROVIDER: S-EPMC5462735 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Wang Jun J Dumartin Laurent L Mafficini Andrea A Ulug Pinar P Sangaralingam Ajanthah A Alamiry Namaa Audi NA Radon Tomasz P TP Salvia Roberto R Lawlor Rita T RT Lemoine Nicholas R NR Scarpa Aldo A Chelala Claude C Crnogorac-Jurcevic Tatjana T
Scientific reports 20170607 1
Despite a wealth of genomic information, a comprehensive alternative splicing (AS) analysis of pancreatic ductal adenocarcinoma (PDAC) has not been performed yet. In the present study, we assessed whole exome-based transcriptome and AS profiles of 43 pancreas tissues using Affymetrix exon array. The AS analysis of PDAC indicated on average two AS probe-sets (ranging from 1-28) in 1,354 significantly identified protein-coding genes, with skipped exon and alternative first exon being the most freq ...[more]