Ontology highlight
ABSTRACT:
SUBMITTER: Tormanen S
PROVIDER: S-EPMC5462783 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Törmänen Sari S Korppi Matti M Teräsjärvi Johanna J Vuononvirta Juho J Koponen Petri P Helminen Merja M He Qiushui Q Nuolivirta Kirsi K
Scientific reports 20170607 1
Toll-like receptors (TLRs) recognise microbes that contribute to the severity of bronchiolitis and the subsequent risk of asthma. We evaluated whether post-bronchiolitis asthma was associated with polymorphisms in the TLR3 rs3775291, TLR4 rs4986790, TLR7 rs179008, TLR8 rs2407992, TLR9 rs187084, and TLR10 rs4129009 genes. The gene polymorphisms were studied at the age of 6.4 years (mean) in 135 children hospitalised for bronchiolitis in infancy. The outcome measure was current or previous asthma. ...[more]