Ontology highlight
ABSTRACT:
SUBMITTER: Mohseni AH
PROVIDER: S-EPMC5464500 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Mohseni Amir Hossein AH Razavilar Vadood V Keyvani Hossein H Razavi Mohammad Reza MR Khavari Nejad Ramazan Ali RA
Asian Pacific journal of cancer prevention : APJCP 20170301 3
HPV 16 intratypic sequence variations has been recognized in association with oncogenic potential diverge and geographic distribution. This study aimed to investigate nucleotide modifications and optimization of HPV 16 E7 regions from Iranian infected women. Cervical biopsies from 79/163 HPV 16 positive cancer patients detected in our study were analyzed by PCR in a couple of cloning of a complete ORF of the E7 gene, and sequencing. The most frequently observed variant was C196T in E7 which led ...[more]