Cancer-derived exosomic microRNAs shape the immune system within the tumor microenvironment: State of the art.
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ABSTRACT:
SUBMITTER: Fanini F
PROVIDER: S-EPMC5466544 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Publications
Cancer-derived exosomic microRNAs shape the immune system within the tumor microenvironment: State of the art.
Fanini Francesca F Fabbri Muller M
Seminars in cell & developmental biology 20161209
In recent years there has been an increasing interest of the scientific community on exosome research, with particular emphasis on the mechanisms by which tumor-derived exosomes can promote tumor growth. Particularly, exosome-mediated immune-escape is under deep investigation and still represents a quite controversial issue. Tumor-derived exosomes are carriers of information able to reprogram functions of immune target cells, influencing their development, maturation, and antitumor activities. T ...[more]
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