Biophysical Mechanisms Mediating Fibrin Fiber Lysis.
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ABSTRACT:
SUBMITTER: Hudson NE
PROVIDER: S-EPMC5467299 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Publications
Biophysical Mechanisms Mediating Fibrin Fiber Lysis.
BioMed research international 20170528
The formation and dissolution of blood clots is both a biochemical and a biomechanical process. While much of the chemistry has been worked out for both processes, the influence of biophysical properties is less well understood. This review considers the impact of several structural and mechanical parameters on lytic rates of fibrin fibers. The influences of fiber and network architecture, fiber strain, FXIIIa cross-linking, and particle transport phenomena will be assessed. The importance of th ...[more]
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