Ontology highlight
ABSTRACT:
SUBMITTER: Liu LL
PROVIDER: S-EPMC5467646 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Liu Lin L LL Brumbaugh Justin J Bar-Nur Ori O Smith Zachary Z Stadtfeld Matthias M Meissner Alexander A Hochedlinger Konrad K Michor Franziska F
Cell reports 20161201 12
Reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) is typically an inefficient and asynchronous process. A variety of technological efforts have been made to accelerate and/or synchronize this process. To define a unified framework to study and compare the dynamics of reprogramming under different conditions, we developed an in silico analysis platform based on mathematical modeling. Our approach takes into account the variability in experimental results stemming from proba ...[more]