Ontology highlight
ABSTRACT: Objective
We introduce descriptor-based segmentation that extends existing patch-based methods by combining intensities, features, and location information. Since it is unclear which image features are best suited for patch selection, we perform a broad empirical study on a multitude of different features.Methods
We extend nonlocal means segmentation by including image features and location information. We search larger windows with an efficient nearest neighbor search based on kd-trees. We compare a large number of image features.Results
The best results were obtained for entropy image features, which have not yet been used for patch-based segmentation. We further show that searching larger image regions with an approximate nearest neighbor search and location information yields a significant improvement over the bounded nearest neighbor search traditionally employed in patch-based segmentation methods.Conclusion
Features and location information significantly increase the segmentation accuracy. The best features highlight boundaries in the image.Significance
Our detailed analysis of several aspects of nonlocal means-based segmentation yields new insights about patch and neighborhood sizes together with the inclusion of location information. The presented approach advances the state-of-the-art in the segmentation of parotid glands for radiation therapy planning.
SUBMITTER: Wachinger C
PROVIDER: S-EPMC5469701 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Wachinger Christian C Brennan Matthew M Sharp Greg C GC Golland Polina P
IEEE transactions on bio-medical engineering 20160916 7
<h4>Objective</h4>We introduce descriptor-based segmentation that extends existing patch-based methods by combining intensities, features, and location information. Since it is unclear which image features are best suited for patch selection, we perform a broad empirical study on a multitude of different features.<h4>Methods</h4>We extend nonlocal means segmentation by including image features and location information. We search larger windows with an efficient nearest neighbor search based on k ...[more]