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Multi-Infarct Dementia: A Historical Perspective.

ABSTRACT: BACKGROUND:Multi-infarct dementia (MID), a prominent subtype of vascular dementia (VaD), has only achieved recognition in the last 4 decades. Since its original description, the characterization, etiological understanding, and therapeutic direction of MID and other VaD subtypes has progressed at an astounding rate. SUMMARY:This paper divides the landmark discoveries and emergence of new research strategies for MID into decade-defining patterns so that a condensed picture of the total history of MID and its eventual inclusion as a VaD subtype emerges. This paper follows the first descriptive decade, a shift to a preventative focus, a renewed interest coinciding with timely advances in research technology, and a hopeful return to treatment possibilities for VaD. KEY MESSAGE:Concisely tracing the historical lineage of the modern understanding of MID, both as a singular entity and as part of the VaD con-stellation of disorders, provides a novel perspective on the foundation upon which future advances in combating vascular contributions to dementia will be based.

SUBMITTER: McKay E

PROVIDER: S-EPMC5471781 | biostudies-literature | 2017 Jan-Apr

REPOSITORIES: biostudies-literature

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Multi-Infarct Dementia: A Historical Perspective.

McKay Erin E Counts Scott E SE

Dementia and geriatric cognitive disorders extra 20170101 1

<h4>Background</h4>Multi-infarct dementia (MID), a prominent subtype of vascular dementia (VaD), has only achieved recognition in the last 4 decades. Since its original description, the characterization, etiological understanding, and therapeutic direction of MID and other VaD subtypes has progressed at an astounding rate.<h4>Summary</h4>This paper divides the landmark discoveries and emergence of new research strategies for MID into decade-defining patterns so that a condensed picture of the to ...[more]

PMID: 28626470

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