Ontology highlight
ABSTRACT:
SUBMITTER: Hardy CJD
PROVIDER: S-EPMC5476347 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Hardy Chris J D CJD Agustus Jennifer L JL Marshall Charles R CR Clark Camilla N CN Russell Lucy L LL Brotherhood Emilie V EV Bond Rebecca L RL Fiford Cassidy M CM Ondobaka Sasha S Thomas David L DL Crutch Sebastian J SJ Rohrer Jonathan D JD Warren Jason D JD
Neurobiology of aging 20170510
The pathophysiology of primary progressive aphasias remains poorly understood. Here, we addressed this issue using activation fMRI in a cohort of 27 patients with primary progressive aphasia (nonfluent, semantic, and logopenic variants) versus 15 healthy controls. Participants listened passively to sequences of spoken syllables in which we manipulated 3-key auditory speech signal characteristics: temporal regularity, phonemic spectral structure, and pitch sequence entropy. Relative to healthy co ...[more]