Ontology highlight
ABSTRACT:
SUBMITTER: Guo J
PROVIDER: S-EPMC5477038 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Guo Jing J Liu Yangbin Y Li Xiangqiang X Liu Xiaohua X Lin Lili L Feng Xiaoming X
Chemical science 20160104 4
A chiral Lewis acid-promoted enantioselective cyclopropanation using phenyliodonium ylide as the carbene precursor was developed. A variety of spirocyclopropane-oxindoles with contiguous tertiary and all carbon quaternary centers were obtained in excellent outcomes (up to 99% yield, >19 : 1 d.r., up to 99% ee). EPR spectroscopy study supported a stepwise biradical mechanism. ...[more]