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Draft Genome Sequence of the Tacrolimus-Producing Bacterium Streptomyces tsukubaensis F601.

ABSTRACT: Streptomyces tsukubaensis strain F601 was found to be a producer of the immunosuppressive drug tacrolimus. The draft genome sequence of this strain was approximately 8.52 Mbp. Genes involved in the biosynthesis of tacrolimus were identified in the genome. This draft genome sequence will provide insights into the genetic basis of tacrolimus biosynthesis and regulation.

SUBMITTER: Zong G

PROVIDER: S-EPMC5477335 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature

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Draft Genome Sequence of the Tacrolimus-Producing Bacterium Streptomyces tsukubaensis F601.

Zong Gongli G Zhong Chuanqing C Fu Jiafang J Qin Ronghuo R Cao Guangxiang G

Genome announcements 20170518 20

Streptomyces tsukubaensis strain F601 was found to be a producer of the immunosuppressive drug tacrolimus. The draft genome sequence of this strain was approximately 8.52 Mbp. Genes involved in the biosynthesis of tacrolimus were identified in the genome. This draft genome sequence will provide insights into the genetic basis of tacrolimus biosynthesis and regulation. ...[more]

PMID: 28522727

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