Ontology highlight
ABSTRACT:
SUBMITTER: Castela M
PROVIDER: S-EPMC5477505 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Nature communications 20170518
Foetal microchimeric cells (FMCs) traffic into maternal circulation during pregnancy and persist for decades after delivery. Upon maternal injury, FMCs migrate to affected sites where they participate in tissue healing. However, the specific signals regulating the trafficking of FMCs to injury sites had to be identified. Here we report that, in mice, a subset of FMCs implicated in tissue repair displays CD11b<sup>+</sup> CD34<sup>+</sup> CD31<sup>+</sup> phenotype and highly express C-C chemokin ...[more]