Ontology highlight
ABSTRACT:
SUBMITTER: Prabhakar A
PROVIDER: S-EPMC5477533 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Prabhakar Arjun A Choi Junhong J Wang Jinfan J Petrov Alexey A Puglisi Joseph D JD
Protein science : a publication of the Protein Society 20170523 7
As the universal machine that transfers genetic information from RNA to protein, the ribosome synthesizes proteins with remarkably high fidelity and speed. This is a result of the accurate and efficient decoding of mRNA codons via multistep mechanisms during elongation and termination stages of translation. These mechanisms control how the correct sense codon is recognized by a tRNA for peptide elongation, how the next codon is presented to the decoding center without change of frame during tran ...[more]