Ontology highlight
ABSTRACT:
SUBMITTER: Liu Y
PROVIDER: S-EPMC5477594 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Liu Yankun Y Zhang Yingnan Y Wu Haidong H Li Yufeng Y Zhang Yi Y Liu Min M Li Xin X Tang Hua H
Cell death & disease 20170406 4
MicroRNAs (miRNAs) have a critical role in tumorigenesis and metastasis, which are major obstacles of cancer therapy. However, the role of miRNAs in colorectal cancer (CRC) metastasis remains poorly understood. Here, we found that miRNA-10a (miR-10a) was upregulated in primary CRC tissues and cell line (SW480) derived from primary CRC compared with metastatic cancer tissues in lymph node and cell line (SW620). The differential expression of miR-10a was inversely correlated with distant metastasi ...[more]