Ontology highlight
ABSTRACT:
SUBMITTER: Riva A
PROVIDER: S-EPMC5479524 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Riva Alice A BØrgesen Michael M Guldmann-Christensen Mariann M Hauge Kyneb Majbritt M Voogd Kirsten K Andersen Christina C Epistolio Samantha S Merlo Elisabetta E Yding Wolff Tine T Hamilton-Dutoit Stephen S Lorenzen Jan J Christensen Ulf Bech UB Frattini Milo M
PloS one 20170621 6
Activating mutations in codon 12 and codon 13 of the KRAS (Kirsten rat sarcoma viral oncogene homolog) gene are implicated in the development of several human cancer types and influence their clinical evaluation, treatment and prognosis. Numerous different methods for KRAS genotyping are currently available displaying a wide range of sensitivities, time to answer and requirements for laboratory equipment and user skills. Here we present SensiScreen® KRAS exon 2 simplex and multiplex CE IVD assay ...[more]