The Association between Pediatric NAFLD and Common Genetic Variants.
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ABSTRACT:
SUBMITTER: Umano GR
PROVIDER: S-EPMC5483624 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Publications
The Association between Pediatric NAFLD and Common Genetic Variants.
Umano Giuseppina Rosaria GR Martino Mariangela M Santoro Nicola N
Children (Basel, Switzerland) 20170618 6
Non-alcoholic fatty liver disease (NAFLD) is one of the most common complications of obesity. Several studies have shown that genetic predisposition probably plays an important role in its pathogenesis. In fact, in the last few years a large number of genetic studies have provided compelling evidence that some gene variants, especially those in genes encoding proteins regulating lipid metabolism, are associated with intra-hepatic fat accumulation. Here we provide a comprehensive review of the ge ...[more]
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