Ontology highlight
ABSTRACT:
SUBMITTER: Huang L
PROVIDER: S-EPMC5486947 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Cell chemical biology 20170518 6
The guanidine-II (mini-ykkC) riboswitch is the smallest of the guanidine-responsive riboswitches, comprising two stem loops of similar sequence. We have solved high-resolution crystal structures of both stem loops for the riboswitch from Gloeobacter violaceus. The stem loops have a strong propensity to dimerize by intimate loop-loop interaction. The dimerization creates specific binding pockets for two guanidine molecules, explaining their cooperative binding. Within the binding pockets the liga ...[more]