Ontology highlight
ABSTRACT:
SUBMITTER: Wang G
PROVIDER: S-EPMC5488652 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Wang Gaochan G Geisbrecht Brian V BV Rueter Christian C Hardwidge Philip R PR
Pathogens (Basel, Switzerland) 20170517 2
Enterotoxigenic <i>Escherichia coli</i> (ETEC) causes childhood diarrhea in developing countries. ETEC strains produce the heat-labile enterotoxin (LT) and/or heat-stable enterotoxins (ST) and encode a diverse set of colonization factors used for adherence to intestinal epithelial cells. We previously found that ETEC secretes a heat-stable protein we designated as ETEC Secreted Factor (ESF) that inhibits the extent of NF-κB activation normally induced by tumor necrosis factor alpha (TNF). Here w ...[more]