Ontology highlight
ABSTRACT:
SUBMITTER: Erclik T
PROVIDER: S-EPMC5489111 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Erclik Ted T Li Xin X Courgeon Maximilien M Bertet Claire C Chen Zhenqing Z Baumert Ryan R Ng June J Koo Clara C Arain Urfa U Behnia Rudy R del Valle Rodriguez Alberto A Senderowicz Lionel L Negre Nicolas N White Kevin P KP Desplan Claude C
Nature 20170111 7637
In the Drosophila optic lobes, 800 retinotopically organized columns in the medulla act as functional units for processing visual information. The medulla contains over 80 types of neuron, which belong to two classes: uni-columnar neurons have a stoichiometry of one per column, while multi-columnar neurons contact multiple columns. Here we show that combinatorial inputs from temporal and spatial axes generate this neuronal diversity: all neuroblasts switch fates over time to produce different ne ...[more]