Ontology highlight
ABSTRACT:
SUBMITTER: Roy LD
PROVIDER: S-EPMC5489651 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Roy Lopamudra Das LD Dillon Lloye M LM Zhou Ru R Moore Laura J LJ Livasy Chad C El-Khoury Joe M JM Puri Rahul R Mukherjee Pinku P
Genes & cancer 20170301 3-4
Screening for breast cancer has predominantly been done using mammography. Unfortunately, mammograms miss 50% cancers in women with dense breast tissue. Multi-modal screenings offer the best chance of enhancing breast cancer screening effectiveness. We evaluated the use of TAB004, an antibody that recognizes the tumor form of the glycoprotein MUC1 (tMUC1), to aid early detection of breast cancer. Our experimental approach was to follow tMUC1 from the tissue into circulation. We found that 95% of ...[more]