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New integron-associated gene cassette encoding a 3-N-aminoglycoside acetyltransferase.

ABSTRACT: A fifth gene cassette containing an aacC gene, aacCA5, was found in an aacCA5-aadA7 cassette array in a class 1 integron isolated from a multiply drug resistant Salmonella enterica serovar Kentucky strain. The AacC-A5 or AAC(3)-Ie acetyltransferase encoded by aacCA5 is related to other AAC(3)-I enzymes and confers resistance to gentamicin.

SUBMITTER: Levings RS 

PROVIDER: S-EPMC549260 | biostudies-literature | 2005 Mar

REPOSITORIES: biostudies-literature

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New integron-associated gene cassette encoding a 3-N-aminoglycoside acetyltransferase.

Levings Renee S RS   Partridge Sally R SR   Lightfoot Diane D   Hall Ruth M RM   Djordjevic Steven P SP  

Antimicrobial agents and chemotherapy 20050301 3

A fifth gene cassette containing an aacC gene, aacCA5, was found in an aacCA5-aadA7 cassette array in a class 1 integron isolated from a multiply drug resistant Salmonella enterica serovar Kentucky strain. The AacC-A5 or AAC(3)-Ie acetyltransferase encoded by aacCA5 is related to other AAC(3)-I enzymes and confers resistance to gentamicin. ...[more]

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