Gut Microbiota Co-microevolution with Selection for Host Humoral Immunity.
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ABSTRACT:
SUBMITTER: Yang L
PROVIDER: S-EPMC5495859 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Publications
Gut Microbiota Co-microevolution with Selection for Host Humoral Immunity.
Yang Lingyu L Liu Shuyun S Ding Jinmei J Dai Ronghua R He Chuan C Xu Ke K Honaker Christa F CF Zhang Yan Y Siegel Paul P Meng He H
Frontiers in microbiology 20170704
To explore coevolution between the gut microbiota and the humoral immune system of the host, we used chickens as the model organism. The host populations were two lines (HAS and LAS) developed from a common founder that had undergone 40 generations of divergent selection for antibody titers to sheep red blood cells (SRBC) and two relaxed sublines (HAR and LAR). Analysis revealed that microevolution of host humoral immunity contributed to the composition of gut microbiota at the taxa level. Relax ...[more]
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