Ontology highlight
ABSTRACT:
SUBMITTER: Carvalho MFNN
PROVIDER: S-EPMC5496576 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Carvalho M Fernanda N N MFNN Herrmann Rudolf R Wagner Gabriele G
Beilstein journal of organic chemistry 20170626
Compounds containing two alkyne groups in close vicinity at the rigid skeleton of camphorsulfonamide show unique reactivities when treated with electrophiles or catalytic amounts of platinum(II). The formed product structures depend not only on the reagents used but also on the substituents attached to the triple bonds. Cycloisomerisations with perfect atom economy lead to polycyclic heterocycles that resemble to some extent the AB ring system of paclitaxel. Herein, we present practical syntheti ...[more]