Ontology highlight
ABSTRACT:
SUBMITTER: Mizoguchi T
PROVIDER: S-EPMC5498671 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Mizoguchi Takahiro T Minakuchi Hiroko H Ishisaka Mitsue M Tsuruma Kazuhiro K Shimazawa Masamitsu M Hara Hideaki H
Scientific reports 20170705 1
VGF nerve growth factor inducible (VGF) is a neuropeptide induced by nerve growth factor and brain-derived neurotrophic factor. This peptide is involved in synaptic plasticity, neurogenesis, and neurite growth in the brain. Patients with depression and bipolar disorder have lower-than-normal levels of VGF, whereas patients with schizophrenia and other cohorts of patients with depression have higher-than-normal levels. VGF knockout mice display behavioral abnormalities such as higher depressive b ...[more]