Ontology highlight
ABSTRACT:
SUBMITTER: Pisanu C
PROVIDER: S-EPMC5502071 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Pisanu Claudia C Preisig Martin M Castelao Enrique E Glaus Jennifer J Pistis Giorgio G Squassina Alessio A Del Zompo Maria M Merikangas Kathleen R KR Waeber Gérard G Vollenweider Peter P Mwinyi Jessica J Schiöth Helgi B HB
Human genetics 20170627 8
Although a number of migraine-associated single-nucleotide polymorphisms (SNP) with small effect size have been identified, little is known about the additive impact of these variants on migraine risk, frequency and severity. We investigated to what extent a genetic risk score (GRS) based on recently published, novel migraine-associated SNPs is associated with migraine prevalence, subtypes and severity in a large population-based sample. The sample comprised 446 subjects with migraine and 2511 c ...[more]