Ontology highlight
ABSTRACT:
SUBMITTER: Song K
PROVIDER: S-EPMC5503553 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Song Kyeongeun K Xu Li L Zhang Wei W Cai Yun Y Jang Bian B Oh Junghwan J Jin Jun-O JO
Oncotarget 20170601 24
This research evaluates the effects of laminarin on the maturation of dendritic cells and on the in vivo activation of anti-cancer immunity. In vivo treatment of C56BL/6 mice with laminarin increased the expression levels of co-stimulatory molecules and the production of pro-inflammatory cytokines in spleen dendritic cells. Laminarin enhanced ovalbumin antigen presentation in spleen dendritic cells and promoted the proliferation of OT-I and OT-II T cells. Laminarin also induced the maturation of ...[more]