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Complete Genome Sequence of Streptococcus thermophilus KLDS 3.1003, A Strain with High Antimicrobial Potential against Foodborne and Vaginal Pathogens.


ABSTRACT: Lactic acid bacteria play increasingly important roles in the food industry. Streptococcus thermophilus KLDS 3.1003 strain was isolated from traditional yogurt in Inner Mongolia, China. It has shown high antimicrobial activity against selected foodborne and vaginal pathogens. In this study, we investigated and analyzed its complete genome sequence. The S. thermophilus KLDS 3.1003 genome comprise of a 1,899,956 bp chromosome with a G+C content of 38.92%, 1,995 genes, and 6 rRNAs. With the exception of S. thermophilus M17TZA496, S. thermophilus KLDS 3.1003 has more tRNAs (amino acid coding genes) compared to some S. thermophilus strains available on the National Centre for Biotechnology Information database. MG-RAST annotation showed that this strain has 317 subsystems with most genes associated with amino acid and carbohydrate metabolism. This strain also has a unique EPS gene cluster containing 23 genes, and may be a mixed dairy starter culture. This information provides more insight into the molecular basis of its potentials for further applications in the dairy and allied industries.

SUBMITTER: Evivie SE 

PROVIDER: S-EPMC5504653 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature

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Complete Genome Sequence of <i>Streptococcus thermophilus</i> KLDS 3.1003, A Strain with High Antimicrobial Potential against Foodborne and Vaginal Pathogens.

Evivie Smith E SE   Li Bailiang B   Ding Xiuyun X   Meng Yueyue Y   Yu Shangfu S   Du Jincheng J   Xu Min M   Li Wan W   Jin Da D   Huo Guicheng G   Liu Fei F  

Frontiers in microbiology 20170711


Lactic acid bacteria play increasingly important roles in the food industry. <i>Streptococcus thermophilus</i> KLDS 3.1003 strain was isolated from traditional yogurt in Inner Mongolia, China. It has shown high antimicrobial activity against selected foodborne and vaginal pathogens. In this study, we investigated and analyzed its complete genome sequence. The <i>S. thermophilus</i> KLDS 3.1003 genome comprise of a 1,899,956 bp chromosome with a G+C content of 38.92%, 1,995 genes, and 6 rRNAs. Wi  ...[more]

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