Dataset Information

Comparative Accuracy of 17 Point-of-Care Glucose Meters.

ABSTRACT:

Background

The accuracy of point-of-care blood glucose (BG) meters is important for the detection of dysglycemia, calculation of insulin doses, and the calibration of continuous glucose monitors. The objective of this study was to compare the accuracy of commercially available glucose meters in a challenging laboratory study using samples with a wide range of reference BG and hemoglobin values.

Methods

Fresh, discarded blood samples from a hospital STAT laboratory were either used without modification, spiked with a glucose solution, or incubated at 37°C to produce 347 samples with an even distribution across reference BG levels from 20 to 440 mg/dl and hemoglobin values from 9 to 16 g/dl. We measured the BG of each sample with 17 different commercially available glucose meters and the reference method (YSI 2300) at the same time. We determined the mean absolute relative difference (MARD) for each glucose meter, overall and stratified by reference BG and by hemoglobin level.

Results

The accuracy of different meters widely, exhibiting a range of MARDs from 5.6% to 20.8%. Accuracy was lower in the hypoglycemic range, but was not consistently lower in samples with anemic blood hemoglobin levels.

Conclusions

The accuracy of commercially available glucose meters varies widely. Although the sample mix in this study was much more challenging than those that would be collected under most use conditions, some meters were robust to these challenges and exhibited high accuracy in this setting. These data on relative accuracy and robustness to challenging samples may be useful in informing the choice of a glucose meter.

SUBMITTER: Ekhlaspour L

PROVIDER: S-EPMC5505415 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature

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Publications

Comparative Accuracy of 17 Point-of-Care Glucose Meters.

Ekhlaspour Laya L Mondesir Debbie D Lautsch Norman N Balliro Courtney C Hillard Mallory M Magyar Kendra K Radocchia Laura Goergen LG Esmaeili Aryan A Sinha Manasi M Russell Steven J SJ

Journal of diabetes science and technology 20161003 3

<h4>Background</h4>The accuracy of point-of-care blood glucose (BG) meters is important for the detection of dysglycemia, calculation of insulin doses, and the calibration of continuous glucose monitors. The objective of this study was to compare the accuracy of commercially available glucose meters in a challenging laboratory study using samples with a wide range of reference BG and hemoglobin values.<h4>Methods</h4>Fresh, discarded blood samples from a hospital STAT laboratory were either used ...[more]

PMID: 27697848

Similar Datasets

Project description:BACKGROUND:Point-of-care haemoglobin meters are attractive solutions to improve timely diagnosis of anaemia in resource-limited settings. However, concerns regarding the accuracy of these meters may affect their adoption. The accuracy of two hand-held point-of-care haemoglobin meters was evaluated against reference full blood count analyser. METHODS:This was a hospital-based cross-sectional study conducted at the Douala General hospital, Cameroon. Two handheld haemoglobin meters were assessed: Urit12® (URIT Medical Electronics Co.,Ltd. Guangxi, China) and MissionHb®(ACON Laboratories, Inc., San Diego, USA); against a reference standard CELL-DYN RUBY® (ABBOTT DIAGNOSTICS, Illinois, USA). The Pearson's correlation and Bland-Altman agreement were used to assess the technical accuracy of the meters. Clinical accuracy was evaluated using total error allowable and area under the Receiver Operating Curve. Finally, their agreement with the reference in diagnosing anaemia was assessed using the kappa statistic. RESULTS:A total of 228 participants were included in the study. The mean haemoglobin values of both haemoglobin meters (MissionHb®: 11.6?±?2.5?g/dl; Urit12®: 10.9?±?2.7?g/dl) were significantly higher than the reference value (10.5?±?2.5?g/dl), p?<?0.001 for both meters. Both haemoglobin meters had good correlation with the reference analyser (r?=?0.89 and r?=?0.90 for Urit12® and MissionHb® respectively) and good agreement on the Bland-Altman plots. However, the MissionHb® meter did not meet the clinical accuracy requirements (p?<?0.001). Even though both meters were excellent at identifying the presence of anemia (MissionHb® - AUC?=?0.9161, Urit 12® - AUC?=?0.9009), they, however, both had weak agreement with the reference analyser in diagnosing the severity of anaemia (K?=?0.39 for MissionHb®, p?<?0.001 and K?=?0.54 for Urit12®, p?<?0.001). CONCLUSION:Although both devices showed technical accuracy with a positive correlation with the reference analyser and were able to accurately diagnose the presence of anemia, both meters however, had sub-optimal agreement with the reference analyser in diagnosing the degree of severity of anaemia among our participants.

Dataset Information

Comparative Accuracy of 17 Point-of-Care Glucose Meters.

Background

Methods

Results

Conclusions

Publications

Comparative Accuracy of 17 Point-of-Care Glucose Meters.

Similar Datasets

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