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Long noncoding RNA expression profile changes associated with dietary energy in the sheep testis during sexual maturation.


ABSTRACT: Spermatogenesis can be affected by nutrition, which operates through normal physiological processes by changing the testicular mass and hormone levels profoundly. However, little is known regarding how testis development is regulated by long noncoding RNA (lncRNA). In this study, we investigated the effects of high-grain (HG) feeding on testis development during sexual maturation mediated by lncRNA. The HG diet group showed an increase in growth hormone (GH), insulin-like growth factor-1 (IGF-1) and testosterone (T) levels, and in the number of sperm in the seminiferous tubules compared with the hay-fed group (p?

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC5507887 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature

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Long noncoding RNA expression profile changes associated with dietary energy in the sheep testis during sexual maturation.

Zhang Yanli Y   Yang Hua H   Han Le L   Li Fengzhe F   Zhang Tingting T   Pang Jing J   Feng Xu X   Ren Caifang C   Mao Shengyong S   Wang Feng F  

Scientific reports 20170712 1


Spermatogenesis can be affected by nutrition, which operates through normal physiological processes by changing the testicular mass and hormone levels profoundly. However, little is known regarding how testis development is regulated by long noncoding RNA (lncRNA). In this study, we investigated the effects of high-grain (HG) feeding on testis development during sexual maturation mediated by lncRNA. The HG diet group showed an increase in growth hormone (GH), insulin-like growth factor-1 (IGF-1)  ...[more]

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