Ontology highlight
ABSTRACT:
SUBMITTER: Munkley J
PROVIDER: S-EPMC5507901 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Scientific reports 20170712 1
Cell migration drives cell invasion and metastatic progression in prostate cancer and is a major cause of mortality and morbidity. However the mechanisms driving cell migration in prostate cancer patients are not fully understood. We previously identified the cancer-associated cell migration protein Tetraspanin 1 (TSPAN1) as a clinically relevant androgen regulated target in prostate cancer. Here we find that TSPAN1 is acutely induced by androgens, and is significantly upregulated in prostate ca ...[more]