Ontology highlight
ABSTRACT:
SUBMITTER: Cressey TR
PROVIDER: S-EPMC5508655 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Cressey Tim R TR Punyawudho Baralee B Le Coeur Sophie S Jourdain Gonzague G Saenjum Chalermpong C Capparelli Edmund V EV Jittayanun Kanokwan K Phanomcheong Siriluk S Luvira Anita A Borkird Thitiporn T Puangsombat Achara A Aarons Leon L Sukrakanchana Pra-Ornsuda PO Urien Saik S Lallemant Marc M
Journal of acquired immune deficiency syndromes (1999) 20170801 5
<h4>Background</h4>Nevirapine (NVP) is a key component of antiretroviral prophylaxis and treatment for neonates. We evaluated current World Health Organization (WHO) weight-band NVP prophylactic dosing recommendations and investigated optimal therapeutic NVP dosing for neonates.<h4>Methods</h4>The PHPT-5 study in Thailand assessed the efficacy of "Perinatal Antiretroviral Intensification" to prevent mother-to-child transmission of HIV in women with <8 weeks of antiretroviral treatment before del ...[more]