Ontology highlight
ABSTRACT:
SUBMITTER: Moreno-Navarrete JM
PROVIDER: S-EPMC5509649 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Moreno-Navarrete José María JM Rodríguez Amaia A Ortega Francisco F Becerril Sara S Sabater-Masdeu Mònica M Latorre Jessica J Ricart Wifredo W Frühbeck Gema G Fernández-Real José Manuel JM
Scientific reports 20170713 1
Iron status is known to be associated with the physiology of adipose tissue (AT). We aimed to investigate AT heme and expression of heme exporter (FLVCR1) in association with obesity and type 2 diabetes (T2D). Substantial amounts of FLVCR1 mRNA and protein levels were detected in AT, being significantly increased in subjects with T2D, and positively correlated with fasting glucose, fasting triglycerides and with circulating markers of iron stores (serum ferritin, blood hemoglobin and hematocrit) ...[more]