Ontology highlight
ABSTRACT:
SUBMITTER: Park IH
PROVIDER: S-EPMC5512366 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Park In Hae IH Sohn Joo Hyuk JH Kim Sung Bae SB Lee Keun Seok KS Chung Joo Seop JS Lee Soo Hyeon SH Kim Tae You TY Jung Kyung Hae KH Cho Eun Kyung EK Kim Yang Soo YS Song Hong Suk HS Seo Jae Hong JH Ryoo Hun Mo HM Lee Sun Ah SA Yoon So Young SY Kim Chul Soo CS Kim Yong Tai YT Kim Si Young SY Jin Mi Ryung MR Ro Jungsil J
Cancer research and treatment 20160912 3
<h4>Purpose</h4>Genexol-PM is a Cremophor EL-free formulation of low-molecular-weight, non-toxic, and biodegradable polymeric micelle-bound paclitaxel. We conducted a phase III study comparing the clinical efficacy and toxicity of Genexol-PM with conventional paclitaxel (Genexol).<h4>Materials and methods</h4>Patients were randomly assigned (1:1) to receive Genexol-PM 260 mg/m<sup>2</sup> or Genexol 175 mg/m<sup>2</sup> intravenously every 3 weeks. The primary outcome was the objective response ...[more]