Ontology highlight
ABSTRACT:
SUBMITTER: Levenson AE
PROVIDER: S-EPMC5513789 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Levenson Amy E AE Shah Amy S AS Khoury Philip R PR Kimball Thomas R TR Urbina Elaine M EM de Ferranti Sarah D SD Maahs David M DM Dolan Lawrence M LM Wadwa R Paul RP Biddinger Sudha B SB
Pediatric diabetes 20170117 8
<h4>Background</h4>Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a key regulator of low-density lipoprotein cholesterol and cardiovascular disease risk, and is an emerging therapeutic target.<h4>Objective</h4>We compared serum PCSK9 levels in young adults, with and without type 2 diabetes.<h4>Subjects and methods</h4>Cross-sectional analysis was conducted in a cohort, aged 15 to 26 years, in Cincinnati, OH, from 2005 to 2010. Serum PCSK9 levels were measured in 94 youth with type 2 di ...[more]