Ontology highlight
ABSTRACT:
SUBMITTER: Wu H
PROVIDER: S-EPMC5515740 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Wu Hong H Jia Xuewen X Zhao Hong H Huang Youmin Y Liu Chang C Huang Zuzhou Z Li Shunjun S Wang Jingli J
Medicine 20170701 28
<h4>Background</h4>SEPP1 encodes selenoprotein P, which involved in oxidative stress and plays an important role in the development of preeclampsia (PE). The aim of this study was to investigate the association between PE and genetic variants of SEPP1 in Chinese Han women.<h4>Methods</h4>In all, 2434 unrelated pregnant women were recruited, including 1034 PE cases and 1400 normal pregnant controls. TaqMan allelic discrimination real-time PCR method was used to genotype the 2 polymorphisms of rs7 ...[more]