Ontology highlight
ABSTRACT:
SUBMITTER: Santarino IB
PROVIDER: S-EPMC5517431 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Santarino Inês B IB Viegas Michelle S MS Domingues Neuza S NS Ribeiro Ana M AM Soares Miguel P MP Vieira Otília V OV
Scientific reports 20170719 1
Erythrophagocytosis, the phagocytic removal of damaged red blood cells (RBC), and subsequent phagolysosome biogenesis are important processes in iron/heme metabolism and homeostasis. Phagolysosome biogenesis implies the interaction of nascent phagosomes with endocytic compartments and also autophagy effectors. Here, we report that besides recruitment of microtubule-associated protein-1-light chain 3 (LC3), additional autophagy machinery such as sequestosome 1 (p62) is also acquired by single-mem ...[more]