Cell-sized mechanosensitive and biosensing compartment programmed with DNA.
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ABSTRACT:
SUBMITTER: Majumder S
PROVIDER: S-EPMC5518703 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Publications
Cell-sized mechanosensitive and biosensing compartment programmed with DNA.
Majumder Sagardip S Garamella Jonathan J Wang Ying-Lin YL DeNies Maxwell M Noireaux Vincent V Liu Allen P AP
Chemical communications (Cambridge, England) 20170601 53
The bottom-up construction of cell-sized compartments programmed with DNA that are capable of sensing the chemical and physical environment remains challenging in synthetic cell engineering. Here, we construct mechanosensitive liposomes with biosensing capability by expressing the E. coli channel MscL and a calcium biosensor using cell-free expression. ...[more]
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