Ontology highlight
ABSTRACT:
SUBMITTER: Terwilliger T
PROVIDER: S-EPMC5520400 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Blood cancer journal 20170630 6
Acute lymphoblastic leukemia (ALL) is the second most common acute leukemia in adults, with an incidence of over 6500 cases per year in the United States alone. The hallmark of ALL is chromosomal abnormalities and genetic alterations involved in differentiation and proliferation of lymphoid precursor cells. In adults, 75% of cases develop from precursors of the B-cell lineage, with the remainder of cases consisting of malignant T-cell precursors. Traditionally, risk stratification has been based ...[more]