Ontology highlight
ABSTRACT:
SUBMITTER: Zhuang L
PROVIDER: S-EPMC5520730 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature
Zhuang Likun L Wang Xin X Wang Zusen Z Ma Xiang X Han Bing B Zou Hao H Wu Zehua Z Dong Sheng S Qu Zhiqiang Z Zang Yunjin Y Wu Liqun L
Cell death & disease 20170518 5
Hepatocellular carcinoma (HCC) is a malignant tumor and threatens human life worldwide, whereas the etiology and pathogenesis of HCC have not been fully determined. In the past few years, many microRNAs (miRNAs) have been proved to have important roles in tumorigenesis of HCC. In this study, we found that miR-23b was significantly upregulated in tumor tissues of HCC patients. Functional tests showed that miR-23b could promote HCC cell proliferation and metastasis in vitro and in vivo. Then, mech ...[more]